PROTAC SMARCA2/4-degrader-28
PROTAC 1 (PROTAC SMARCA2/4-degrader-28) is a heterobifunctional molecule that induces partial degradation of the SMARCA2 and SMARCA4 bromodomain proteins via the ubiquitin-proteasome system. This tool compound is used in vitro and in vivo to probe the roles of these ATPases in cancer research and synthetic lethality studies.
Product Specifications
CAS Number
2409844-88-6
Field of Research
Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery
Smiles
CC=1C2=C (N3C ([C@H] (CC (N[C@@H]4COCCOCCOC=5C (=CC=C (C5) C6=C (C) N=CS6) CNC (=O) [C@]7 (N (C (=O) [C@H] ([C@] (C) (C) C) NC (=O) COCCOCCOC4) C[C@H] (O) C7) [H]) =O) N=C2C8=CC=C (Cl) C=C8) =NN=C3C) SC1C
Molecular Formula
C54H68ClN9O11S2
Molecular Weight
1118.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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