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PAR4 antagonist 6

Compound 12 is a potent small molecule antagonist of protease-activated receptor 4 (PAR4), demonstrating inhibitory activity with IC50 values of 134 nM for human PAR4 and 150 nM for mouse PAR4. This tool compound is suitable for investigating PAR4-mediated signaling in thrombosis, inflammation, and cancer research across both in vitro cellular assays and in vivo disease models.

Product Specifications

Field of Research

Pharmacology & Drug Discovery

Molecular Formula

C16H14F2N6O

Molecular Weight

344.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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