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PF-07899895

PF-07899895 is a potent and selective salt-inducible kinase (SIK) inhibitor, exhibiting IC50 values of 1.2 nM, 0.9 nM, and 1.8 nM against SIK1, SIK2, and SIK3, respectively. This tool compound is useful for investigating SIK signaling in immunology, metabolism, and cancer research in both cellular and in vivo models.

Product Specifications

CAS Number

3033846-10-2

Field of Research

Signal Transduction

Purity

99.81% (May vary between batches)

Smiles

N#CC1=CC=CC2=NC=C (C=3C=C (OCC4 (N) CCCCC4) C (C#N) =C (SC) C3) N12

Molecular Formula

C23H23N5OS

Molecular Weight

417.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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