PF-07899895
PF-07899895 is a potent and selective salt-inducible kinase (SIK) inhibitor, exhibiting IC50 values of 1.2 nM, 0.9 nM, and 1.8 nM against SIK1, SIK2, and SIK3, respectively. This tool compound is useful for investigating SIK signaling in immunology, metabolism, and cancer research in both cellular and in vivo models.
Product Specifications
CAS Number
3033846-10-2
Field of Research
Signal Transduction
Purity
99.81% (May vary between batches)
Smiles
N#CC1=CC=CC2=NC=C (C=3C=C (OCC4 (N) CCCCC4) C (C#N) =C (SC) C3) N12
Molecular Formula
C23H23N5OS
Molecular Weight
417.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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