S-WJM992

S-WJM992 (compound 10ahb) is a dual-action antimalarial agent that inhibits parasite Na+-ATPase activity, including in PfATP4-inhibitor resistant strains. It also functions as a transmission-blocking compound by disrupting gametocyte development, preventing mosquito infection. This makes it a valuable tool for studying malaria parasite biology and drug resistance mechanisms in both in vitro and in vivo models.