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MPO-IN-8

MPO-IN-8 is an orally bioavailable small molecule inhibitor of myeloperoxidase (MPO) . It effectively suppresses hypochlorous acid generation and NETosis in neutrophils, and has demonstrated in vivo efficacy in reducing inflammation, peroxidase activity, and IL-1β in a murine model of gouty arthritis.

Product Specifications

CAS Number

62578-87-4

Field of Research

Metabolism Research

Smiles

O=C1C=2C=CC=C3C=C (N) C=C (C (=O) N1N) C32

Molecular Formula

C12H9N3O2

Molecular Weight

227.22

Storage Conditions

-20°C

Notes

For research use only.

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