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NLRP3-IN-45

NLRP3-IN-45 (D6) is a potent and selective NLRP3 inflammasome inhibitor, with an IC50 of 41.79 nM against IL-1β. It blocks inflammasome assembly without affecting priming and has demonstrated efficacy in an LPS-induced acute lung injury (ALI) mouse model, supporting its use in researching NLRP3-driven inflammatory diseases.

Product Specifications

Field of Research

Cell Biology, Immunology & Inflammation

Molecular Formula

C27H30FNO6

Molecular Weight

483.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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