NLRP3-IN-45
NLRP3-IN-45 (D6) is a potent and selective NLRP3 inflammasome inhibitor, with an IC50 of 41.79 nM against IL-1β. It blocks inflammasome assembly without affecting priming and has demonstrated efficacy in an LPS-induced acute lung injury (ALI) mouse model, supporting its use in researching NLRP3-driven inflammatory diseases.
Product Specifications
Field of Research
Cell Biology, Immunology & Inflammation
Molecular Formula
C27H30FNO6
Molecular Weight
483.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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