NCAO
N-ω-chloroacetyl-L-ornithine (NCAO) is a potent, reversible competitive inhibitor of ornithine decarboxylase (ODC) with cytotoxic and antiproliferative effects in tumor cell lines (EC50 1-50.6 μM) . It induces apoptosis, inhibits migration in vitro, and shows significant antitumor efficacy in mouse models of solid and ascitic myeloma tumors, supporting its use in oncology research.
Product Specifications
CAS Number
20584-81-0
Field of Research
Cell Biology
Smiles
C ([C@@H] (C (O) =O) N) CCNC (CCl) =O
Molecular Formula
C7H13ClN2O3
Molecular Weight
208.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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