JNK-1-IN-3
JNK-1-IN-3 (Compound 9e) is a potent and selective JNK1 inhibitor that suppresses the JNK/c-Jun signaling pathway and reactivates p53. It demonstrates significant antiproliferative effects in renal and breast cancer cell lines in vitro, supporting its use as a research tool in oncology and signal transduction studies.
Product Specifications
CAS Number
3056388-71-4
Field of Research
Cell Biology, Protein Biochemistry, Signal Transduction
Purity
97.55% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (13.57 mM) ; DMSO:80 mg/mL (217.18 mM)
Smiles
O=C (NNC=1N=NC (=CC1) C2=CC=C (OC) C (OC) =C2) C3=CC=C (F) C=C3
Molecular Formula
C19H17FN4O3
Molecular Weight
368.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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