PARP1-IN-27
PARP1-IN-27 (Compound 9B) is a potent dual PARP1/2 inhibitor with low nanomolar IC50 values. It demonstrates anti-proliferative activity in BRCA-mutant cell lines by inducing DNA damage, ROS, G2/M arrest, and apoptosis, supporting its use in oncology research for studying DNA repair mechanisms and synthetic lethality.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Molecular Biology, Signal Transduction
Molecular Formula
C17H12FNO4
Molecular Weight
313.28
Storage Conditions
-20°C
Notes
For research use only.
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