Cernuumolide J
Cernuumolide J (TMJ-105) is a potent JAK2/STAT3 signaling inhibitor with an IC50 of 1.79 μM against HEL leukemia cells, inducing G2/M arrest and apoptosis. Its anti-cancer activity, demonstrated in vitro, involves modulating MAPK pathways, making it a candidate for research in hematological malignancies and JAK/STAT-driven cancers.
Product Specifications
CAS Number
2019163-02-9
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O (C (C (C) C) =O) [C@@H]1[C@@]2 ([C@@] ([C@H] (OC (/C (=C\C) /C) =O) C (=O) [C@H] (C) CCC[C@]1 (C) O) (C (=C) C (=O) O2) [H]) [H]
Molecular Formula
C24H34O8
Molecular Weight
450.52
Storage Conditions
-20°C
Notes
For research use only.
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