BTK-IN-37

BTK-IN-37 (compound 8d) is a potent and selective BTK inhibitor with K_i and IC_50 values in the low nanomolar range. It induces cancer cell apoptosis and modulates gene expression to promote necroptosis and pyroptosis pathways. This small molecule is a valuable research tool for studying BTK-dependent signaling in hematological and solid tumor models, both in vitro and in vivo.