KUNG65
KUNG65 is a potent and selective small molecule inhibitor of Grp94 (Hsp90B1) with a K_d of 540 nM, showing over 73-fold selectivity versus other Hsp90 isoforms. This tool compound is useful for studying Grp94-specific biology in cancer, inflammation, and autoimmune disease research, both in cellular and biochemical assays.
Product Specifications
CAS Number
2144469-30-5
Field of Research
Metabolism Research, Signal Transduction
Smiles
O=C (OC) C=1C (O) =CC (O) =C (Cl) C1CCC=2C=CC=CC2CC3=CC=C (F) C=C3
Molecular Formula
C23H20ClFO4
Molecular Weight
414.85
Storage Conditions
-20°C
Notes
For research use only.
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