Antimalarial agent 42

Compound 42 (Compound 2) is a potent antimalarial small molecule with sub-micromolar activity against both asexual blood stages (IC50 <0.5 μM) and gametocytes (IC50 0.14 μM) of Plasmodium falciparum. It is a valuable research tool for investigating malaria parasite biology and for in vitro assays in drug discovery.