GSI-18
GSI-18 is a γ-secretase inhibitor that blocks Notch signaling, thereby suppressing anchorage-independent growth in pancreatic cancer cells. This small molecule is a valuable research tool for investigating Notch pathway roles in pancreatic cancer, with applications in both in vitro and in vivo oncology studies.
Product Specifications
CAS Number
362653-62-1
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Smiles
N (S (=O) (=O) C1=CC=CS1) [C@H]2[C@]3 (CC=4C (C[C@@]2 (CC3) [H]) =CC=CC4) [H]
Molecular Formula
C17H19NO2S2
Molecular Weight
333.47
Storage Conditions
-20°C
Notes
For research use only.
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