Thalidomide-N-methylpiperazine
Thalidomide-N-methylpiperazine serves as an E3 ligase ligand-linker conjugate for constructing PROTAC MLKL Degrader-2. This molecule exhibits antinecroptotic function in human cell lines and has been shown to degrade MLKL in the HT-29 xenograft mouse model, supporting research in targeted protein degradation and necroptosis.
Product Specifications
CAS Number
2924858-30-8
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1NC (=O) C (N2C (=O) C3=CC=C (C=C3C2=O) N4CCN (C) CC4) CC1
Molecular Formula
C18H20N4O4
Molecular Weight
356.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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