ZX782
ZX782 is a small molecule GPX4 degrader that induces ferroptosis by promoting GPX4 destruction via the ubiquitin-proteasome and autophagy-lysosome pathways. This action leads to lethal lipid ROS accumulation in cells like HT1080, making it a valuable tool for studying ferroptosis in cancer research and related in vitro models.
Product Specifications
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Molecular Formula
C39H48ClN5O8
Molecular Weight
750.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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