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ZX782

ZX782 is a small molecule GPX4 degrader that induces ferroptosis by promoting GPX4 destruction via the ubiquitin-proteasome and autophagy-lysosome pathways. This action leads to lethal lipid ROS accumulation in cells like HT1080, making it a valuable tool for studying ferroptosis in cancer research and related in vitro models.

Product Specifications

Field of Research

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Molecular Formula

C39H48ClN5O8

Molecular Weight

750.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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