XMD15-44
XMD15-44 is a potent and selective RET kinase inhibitor, demonstrating low nanomolar IC50 values against RET/C634R (11.5 nM) and RET/M918T (8.3 nM) driven models. It effectively blocks RET-driven signaling and proliferation in thyroid cancer cell lines, making it a valuable tool for in vitro oncogenic RET research.
Product Specifications
CAS Number
1240489-67-1
Field of Research
Cell Biology, Signal Transduction
Smiles
O=C (NC1=CC=C (C (=C1) C (F) (F) F) CN2CCN (CC) CC2) C3=CC=C (C (C#CC=4C=NC=CC4) =C3) C
Molecular Formula
C29H29F3N4O
Molecular Weight
506.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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