JBJ-08-178-01
JBJ-08-178-01 is a mutant-selective HER2 tyrosine kinase inhibitor that induces proteasomal degradation of the receptor, reducing its kinase activity and protein levels. It has demonstrated antitumor activity in non-small cell lung cancer research, showing promise in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2401867-58-9
Field of Research
Protein Biochemistry
Smiles
N (C=1C2=C (C=C (OCC) C (NC (/C=C/CN (C) C) =O) =C2) N=CC1C#N) C3=CC (C) =C (OC4=CC=5N (C=C4) N=CN5) C=C3
Molecular Formula
C31H30N8O3
Molecular Weight
562.62
Storage Conditions
-20°C
Notes
For research use only.
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