WB436B
WB436B is a potent and selective STAT3 inhibitor that blocks STAT3-Tyr705 phosphorylation and downstream target gene expression. It induces apoptosis in pancreatic cancer cells in vitro and has demonstrated efficacy in suppressing tumor growth and metastasis in mouse models, supporting its use in oncology research.
Product Specifications
CAS Number
2248552-84-1
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
N#CC1=C (SC2=C1CCN (C (=O) NC=3C=CC=CC3OC) C2) NC (=O) C=4C=NN (C4) C
Molecular Formula
C21H20N6O3S
Molecular Weight
436.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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