SJ-C1044
SJ-C1044 is an orally active pan-RAF inhibitor with additional activity against VEGFR2, TIE2, and CSF1R. It suppresses tumor growth by inhibiting the MAPK pathway and modulates the tumor immune microenvironment, making it a candidate for research in colorectal cancer models both in vitro and in vivo.
Product Specifications
CAS Number
2121503-76-0
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C (NC1=CC (=CC=C1F) NC2=NC=CC=C2C=3N=CN=C4N=CNC43) C=5C=C (C=C (C5) C (F) (F) F) C (F) (F) F
Molecular Formula
C25H14F7N7O
Molecular Weight
561.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
037968-AP 200 µL
LRRC6, ID (LRRC6, LRTP, TSLRP, Protein TILB homolog, Leucine-rich repeat-containing protein 6, Leucine-rich testis-specific protein, Testis-specific leucine-rich repeat protein) (AP) discontinued
Sign In for Pricing
View Details 
MBS1260696-01 0.02 mg (E-Coli)
Recombinant Giardia intestinalis Basic immunoglobulin-like variable motif-containing protein (BIVM)
Sign In for Pricing
View Details