SJ-C1044
SJ-C1044 is an orally active pan-RAF inhibitor with additional activity against VEGFR2, TIE2, and CSF1R. It suppresses tumor growth by inhibiting the MAPK pathway and modulates the tumor immune microenvironment, making it a candidate for research in colorectal cancer models both in vitro and in vivo.
Product Specifications
CAS Number
2121503-76-0
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C (NC1=CC (=CC=C1F) NC2=NC=CC=C2C=3N=CN=C4N=CNC43) C=5C=C (C=C (C5) C (F) (F) F) C (F) (F) F
Molecular Formula
C25H14F7N7O
Molecular Weight
561.41
Storage Conditions
-20°C
Notes
For research use only.
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