TETi76
TETi76 is an orally bioavailable, competitive pan-TET enzyme inhibitor with IC50 values of 1.5-9.4 μM. It selectively reduces 5hmC and suppresses clonal growth in TET2-mutant models, making it a valuable chemical probe for studying epigenetic mechanisms in leukemia, both in vitro and in vivo.
Product Specifications
CAS Number
1451750-73-4
Field of Research
Epigenetics & Chromatin
Smiles
O=C (OCC) C (=C) CC (O) C (=O) OCC
Molecular Formula
C10H16O5
Molecular Weight
216.23
Storage Conditions
-20°C
Notes
For research use only.
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