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TETi76

TETi76 is an orally bioavailable, competitive pan-TET enzyme inhibitor with IC50 values of 1.5-9.4 μM. It selectively reduces 5hmC and suppresses clonal growth in TET2-mutant models, making it a valuable chemical probe for studying epigenetic mechanisms in leukemia, both in vitro and in vivo.

Product Specifications

CAS Number

1451750-73-4

Field of Research

Epigenetics & Chromatin

Smiles

O=C (OCC) C (=C) CC (O) C (=O) OCC

Molecular Formula

C10H16O5

Molecular Weight

216.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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