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AJI-214

AJI-214 is a dual Aurora kinase A and JAK2 inhibitor that disrupts T-cell mitosis and STAT3 signaling, thereby reducing TH1/TH17 cell differentiation. It is a research tool for studying immune modulation and has been investigated in preclinical models of graft-versus-host disease (GVHD) .

Product Specifications

CAS Number

1395886-20-0

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Smiles

O=C (N) C1=CC=C (C=C1) NC2=NC=C (F) C (=N2) NC=3C=CC=CC3Cl

Molecular Formula

C17H13ClFN5O

Molecular Weight

357.77

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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