AMI-408
AMI-408 is a potent and selective PRMT1 inhibitor. It effectively diminishes asymmetric dimethylation of histone H4 at arginine 3 (H4R3me2a) in MLL-rearranged leukemia models. This tool compound is useful for investigating epigenetic mechanisms in cancer research, both in vitro and in vivo.
Product Specifications
CAS Number
78866-14-5
Field of Research
Epigenetics & Chromatin
Smiles
O=S ([O-]) (C1=C (N=NC2=CC=C (C=C2) OC) C (O) =C3C=CC (NC4=NC (Cl) =NC (Cl) =N4) =CC3=C1) =O.[Na+]
Molecular Formula
C20H13Cl2N6NaO5S
Molecular Weight
543.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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