BRD8518
BRD8518 is a potent small molecule PCSK9 inhibitor (EC50=0.23 μM) used in cardiovascular research. It functions by upregulating LDL receptor expression to enhance LDL uptake, thereby lowering lipid levels in experimental models for atherosclerosis and hypercholesterolemia studies.
Product Specifications
CAS Number
1565828-01-4
Field of Research
Metabolism Research
Smiles
O=C1C=2C (OC[C@]3 ([C@@] (N1C) (CC[C@@H] (CC (NC4CC=5C (C4) =CC=CC5) =O) O3) [H]) [H]) =CC=C (NC (=O) C6=CC=C (C (F) (F) F) C=C6) C2
Molecular Formula
C33H32F3N3O5
Molecular Weight
607.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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