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BRD8518

BRD8518 is a potent small molecule PCSK9 inhibitor (EC50=0.23 μM) used in cardiovascular research. It functions by upregulating LDL receptor expression to enhance LDL uptake, thereby lowering lipid levels in experimental models for atherosclerosis and hypercholesterolemia studies.

Product Specifications

CAS Number

1565828-01-4

Field of Research

Metabolism Research

Smiles

O=C1C=2C (OC[C@]3 ([C@@] (N1C) (CC[C@@H] (CC (NC4CC=5C (C4) =CC=CC5) =O) O3) [H]) [H]) =CC=C (NC (=O) C6=CC=C (C (F) (F) F) C=C6) C2

Molecular Formula

C33H32F3N3O5

Molecular Weight

607.62

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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