EN171
EN171 is a covalent molecular glue that selectively targets 14-3-3 proteins, enhancing their interactions with client proteins like ERα, YAP, and TAZ to disrupt oncogenic transcriptional pathways. It also serves as a recruiter in heterobifunctional molecules for the cytosolic sequestration of nuclear targets such as BRD4, applicable in cancer research and targeted protein degradation studies.
Product Specifications
CAS Number
2191110-79-7
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Smiles
O=C (C=C) N1CCC2 (C1) CN (CC=3C=CC=CC3) CC2
Molecular Formula
C17H22N2O
Molecular Weight
270.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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