CDK-IN-14

CDK-IN-14 (B34) is a potent and selective CDK2 inhibitor (IC50=0.097 μM) with demonstrated anti-hepatocellular carcinoma activity. In vitro, it induces cell cycle arrest and caspase-mediated apoptosis in HepG-2 cells, supporting its use in oncology research focused on cell cycle regulation and apoptosis mechanisms.