SHP2-IN-32
SHP2-IN-32 (C6) is a potent, orally bioavailable allosteric inhibitor of SHP2 with an IC50 of 0.13 nM. It is a research tool for investigating SHP2-dependent signaling in oncology, demonstrating antitumor efficacy in both cellular assays and in vivo models.
Product Specifications
CAS Number
3043685-80-6
Field of Research
Metabolism Research, Signal Transduction
Smiles
N[C@H]1C2 (CC=3C1=CC=CC3) CCN (CC2) C=4C=NC (SC5=C (Cl) C (NC (=O) C=6C (O) =CC=NC6) =CC=C5) =CN4
Molecular Formula
C29H27ClN6O2S
Molecular Weight
559.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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