And1 degrader 1
And1 degrader 1 (Compound A15) is a small molecule that induces the degradation of the And1 protein. It demonstrates synergistic anti-proliferative activity with Olaparib in NSCLC cell lines like A549 and H460, making it a useful chemical probe for oncology research, particularly in studying DNA replication and repair pathways.
Product Specifications
CAS Number
3029132-46-2
Field of Research
Cell Biology, Molecular Biology
Smiles
N (CC1=CC (/C=C/C2=CC (Cl) =C (Cl) C=C2) =CC=C1O) C3=CC=C (C=C3) N4CCN (C) CC4
Molecular Formula
C26H27Cl2N3O
Molecular Weight
468.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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