(-) -5-HT2C agonist-3

(-) -19 is a selective 5-HT2C receptor agonist with a Gq signaling bias, showing EC50 values of 103 nM (5-HT2C), 570 nM (5-HT2B), and 72 nM (5-HT2A) . It is a research tool used in vitro and in vivo for studying antipsychotic mechanisms and serotonin receptor pharmacology.