SILA-123
SILA-123 is a potent and selective FLT3 inhibitor (IC50=2.1 nM for FLT3-WT, 1.0 nM for FLT3-ITD) used in acute myeloid leukemia research. It induces apoptosis and G0/G1 cell cycle arrest by blocking FLT3 phosphorylation and downstream signaling, as demonstrated in cellular studies.
Product Specifications
CAS Number
2911585-37-8
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C (NC=1C=CC (=CC1) C=2C=C (N=C3ON=C (N) C32) C) NC4=CC=C (C=C4) C (C) (C) C
Molecular Formula
C24H25N5O2
Molecular Weight
415.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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