LpxC-IN-15

LpxC-IN-15 ((S) -13j) is a potent small-molecule inhibitor of LpxC, demonstrating high affinity with Ki values of 9.05 nM (EcLpxC C63A) and 5.6 nM (PaLpxC) . This compound exhibits antibacterial activity and serves as a valuable research tool for studying Gram-negative bacterial infections in biochemical and microbiological assays.