Multi-kinase inhibitor 3

Multi-kinase inhibitor 3 (compound 12) is a potent, orally bioavailable small molecule targeting key receptor tyrosine kinases including VEGFRs, FLT3, and PDGFRs with sub-nanomolar IC50 values. It demonstrates robust anti-proliferative effects in cellular assays and has shown efficacy in preclinical in vivo cancer models, supporting its use in oncology and angiogenesis research.