Antiproliferative agent-57
Antiproliferative agent-57 (M2) is a non-cytotoxic small molecule inhibitor of tumor angiogenesis with an IC50 of 0.68 μM in SiHa cells. It functions by suppressing hypoxia-induced VEGF secretion via modulation of the PI3K/AKT/mTOR and MAPK pathways, leading to reduced HIF-1α expression, as demonstrated in cellular and tissue-based research models.
Product Specifications
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.
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