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PROTAC 20S proteasome subunit β5 degrader 2

PROTAC 20S proteasome subunit β5 degrader 2 is a potent and selective degrader (DC50 = 0.16 μM) of the 20S proteasome's β5 subunit. It demonstrates anti-proliferative activity in FaDu cancer cells (IC50 = 0.23 μM) and has shown in vivo antitumor efficacy in mouse models, supporting its use in oncology and targeted protein degradation research.

Product Specifications

Field of Research

Pharmacology & Drug Discovery, Protein Biochemistry

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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