NOD1/2-IN-1

NOD1/2-IN-1 (Compound 18) is a highly potent, dual inhibitor of RIPK2 (IC50=1.4 nM) and the NOD1/NOD2 signaling pathways. It effectively suppresses pro-inflammatory cytokine production and is a valuable research tool for studying inflammatory diseases, including experimental models of colitis, in both cellular and in vivo contexts.