PROTAC GSPT1 degrader-1
PROTAC GSPT1 degrader-1 (Compound F) is a potent and selective degrader of GSPT1, achieving >95% degradation at 1 μM. It demonstrates potent anti-proliferative activity in HL-60 cells (IC50 = 9.2 nM) and is a valuable chemical tool for studying targeted protein degradation in oncology research, including in vitro mechanistic studies.
Product Specifications
CAS Number
3034310-17-0
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1NC (=O) C (N2C (=O) C3=CC=C (C=C3C2=O) N4CC (C4) CCN5C (=O) N (C=6C=CC=C (C6) C=7C=NC=8NC=C (C8C7Cl) CC) CCC5) CC1
Molecular Formula
C37H36ClN7O5
Molecular Weight
694.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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