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10-Methoxy-canthin-6-one

10-Methoxy-canthin-6-one is a DNA-intercalating agent that induces DNA damage, leading to G2/M cell cycle arrest and subsequent differentiation in acute myeloid leukemia (AML) and leukemia stem cells (LSCs) . This small molecule is a valuable research tool for studying myeloid differentiation and p38 MAPK signaling in both in vitro and in vivo leukemia models.

Product Specifications

CAS Number

86293-40-5

Field of Research

Signal Transduction

Smiles

O=C1C=CC2=NC=CC=3C4=CC (OC) =CC=C4N1C23

Molecular Formula

C15H10N2O2

Molecular Weight

250.25

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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