DCAF1 ligand 1
DCAF1 Ligand 1 (I-653) is the target-binding ligand for the PROTAC CBRD4-DCAF1 degrader-1, demonstrating potent degradation activity with a DC50 in the 10-100 nM range. This compound is a valuable chemical tool for targeted protein degradation research in both cellular and in vivo models to study BRD4 biology and related pathways.
Product Specifications
CAS Number
3036941-01-9
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
C (=O) (C1=C (C (C (N[C@@H] (CC (N) =O) C2=CC (Cl) =CC=C2) =O) =CN1) C3=C (C) C (F) =CC=C3F) C4=CC=CC=C4
Molecular Formula
C28H22ClF2N3O3
Molecular Weight
521.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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