Antifungal agent 117

Antifungalagent 117 is a bipyrrole carboxamide derivative with potent activity against Sclerotinia sclerotiorum (EC50 11.58 mg/L) . It induces fungal cell death by disrupting membrane integrity through ROS accumulation and altered ceramide metabolism, as shown by RNA-seq. This mechanism supports its research potential for in vitro studies and agricultural antifungal applications.