RIPK1-IN-25

RIPK1-IN-25 (WL8) is a potent, brain-penetrant small molecule inhibitor of RIPK1, with an EC50 of 19.9 nM and a Kd of 25 nM. It is a valuable research tool for investigating RIPK1's role in neurodegenerative disease models, supporting both in vitro mechanistic studies and in vivo preclinical research.