PROTAC BRD4-DCAF1 degrader-1
PROTACBRD4-DCAF1 degrader-1 (I-907) is a potent heterobifunctional degrader that selectively targets BRD4 for proteasomal degradation via the DCAF1 E3 ligase, with a DC50 typically between 10 and 100 nM. It is a valuable chemical tool for studying BRD4 biology and targeted protein degradation in both cellular and in vivo cancer research models.
Product Specifications
CAS Number
3036944-87-0
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
CC=1C2=C (N3C ([C@H] (CC (NCCOCCOCCOCCOCCOCCCC4=CC=C (C (=O) C5=C (C (C (N[C@@H] (CC (N) =O) C6=CC (Cl) =CC=C6) =O) =CN5) C7=C (C) C (F) =CC=C7F) C=C4) =O) N=C2C8=CC=C (Cl) C=C8) =NN=C3C) SC1C
Molecular Formula
C60H64Cl2F2N8O9S
Molecular Weight
1182.17
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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