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BPU17

BPU17 is a small molecule research agent that disrupts the PHB1-PHB2 complex, leading to mitochondrial impairment and subsequent inhibition of SRF/CArG-dependent transcription and EMT in RPE cells. It has shown anti-fibrotic efficacy in vivo, highlighting its potential for studying pathological processes in neovascular age-related macular degeneration (nAMD) .

Product Specifications

CAS Number

2198977-68-1

Field of Research

Metabolism Research

Smiles

O=C (NC1=CC=C (Cl) C=C1) NC (=O) C2CCC2

Molecular Formula

C12H13ClN2O2

Molecular Weight

252.70

Storage Conditions

-20°C

Notes

For research use only.

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