GDCNF-11
GDCNF-11 is an HSP90-based HIM-PROTAC that induces ferroptosis by degrading GPX4, with a DC50 of 0.08 μM in HT-1080 cells. This tool compound is used in vitro to study ferroptosis mechanisms and explore therapeutic strategies for cancer research.
Product Specifications
CAS Number
2991588-80-6
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C (NCCC=1C=CC=CC1) C (C=2SC=CC2) N (C (=O) CCl) C3=CC=C (OCC=4N=NN (C4) CC (=O) N5CCC (CCNC6=NC (=NC7=C6N=CN7CC8=NC=C (C (OC) =C8C) C) N) CC5) C (Cl) =C3
Molecular Formula
C48H53Cl2N13O5S
Molecular Weight
994.99
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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