AChE-IN-77

AChE-IN-77 (5d) is a dual inhibitor of acetylcholinesterase (AChE; IC50 = 29.46 μM) and β-secretase 1 (BACE1; IC50 = 2.85 μM), with additional in vitro Fe3+ chelating activity. This profile makes it a useful research tool for investigating multifactorial targets in neurodegenerative disease models, including Alzheimer's disease.